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发表于 2013-4-8 12:37:03
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流式中文网CD分子数据库今日更新至CD249。
http://www.flowcyto.cn/bbs/cluster.php?mod=cdlist&page=8
CD249
【中文描述】
谷氨酰氨肽酶又称氨肽酶A,是一种由ENPEP基因编码的酶。谷氨酰氨肽酶最近才被命名为CD249(白细胞分化抗原249)。
谷氨酰氨肽酶是一种锌依赖的细胞膜结合的氨肽酶,催化谷氨酸和天冬氨酸的氨基残基从多肽的N-末端剪切下来。该酶可将负责血管收缩的血管紧张素II降解为血管紧张素Ⅲ,因此有助于调节血压。
【英文描述】
Glutamyl aminopeptidase also known as aminopeptidase A is an enzyme encoded by the ENPEP gene. Glutamyl aminopeptidase has also recently been designated CD249 (cluster of differentiation 249).
Glutamyl aminopeptidase is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of glutamatic and aspartatic amino acid residues from the N-terminus of polypeptides. The enzyme degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure. |
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