新手请教PBMC周期检测

niwanmao

闷油瓶 发表于 2023-3-9 20:21
您了解不了解，有没有那种专门抑制T细胞或者淋巴细胞的物质？专门促使这种细胞凋亡的 ...

你看看Bing的回答是否靠谱，通过相关链接去确认一下：
1、色氨酸剥夺
2、干细胞产物中的单核细胞
3、间充质干细胞


- Tryptophan deprivation can sensitize activated T cells to apoptosis by reducing their expression of anti-apoptotic proteins and enhancing their susceptibility to Fas-mediated death¹.
- Monocytes derived from stem cell products can inhibit T cell proliferation by inducing the apoptosis of activated T cells and natural killer cells through a mechanism involving nitric oxide².
- Mesenchymal stem cells can inhibit T cell proliferation by direct cell-to-cell contact or by secreting soluble factors such as prostaglandin E2, indoleamine 2,3-dioxygenase and transforming growth factor-beta⁴.

(1) Tryptophan deprivation sensitizes activated T cells to apoptosis prior .... https://pubmed.ncbi.nlm.nih.gov/12460190/ Accessed 2023/3/10.
(2) Activation-induced T cell apoptosis by monocytes from stem cell .... https://pubmed.ncbi.nlm.nih.gov/11460311/ Accessed 2023/3/10.
(3) T Cell Proliferation - an overview | ScienceDirect Topics. https://www.sciencedirect.com/to ... -cell-proliferation Accessed 2023/3/10.
(4) Programmed Cell Death (Apoptosis) - Molecular Biology of the Cell .... https://www.ncbi.nlm.nih.gov/books/NBK26873/ Accessed 2023/3/10.
(5) Tryptophan deprivation sensitizes activated T cells to apoptosis prior .... https://pubmed.ncbi.nlm.nih.gov/12460190/ Accessed 2023/3/10.

闷油瓶

niwanmao 发表于 2023-3-10 08:28
你看看Bing的回答是否靠谱，通过相关链接去确认一下：
1、色氨酸剥夺
2、干细胞产物中的单核细胞

多谢，辛苦了，我这个英文菜鸟多多努力